Hi Zach,
There is an article on this here:
https://extremeportal.force.com/ExtrArticleDetail?an=000078659
This will permit/deny access to the EXOS Web GUI itself. Note that this does not apply to SSH/Telnet/SNMP, which have access-profiles of their own, search our user guide or the knowledge base for more details there.
Regarding your XMC/NAC setup, I believe that XMC now does a lot of polling via the switch's RESTAPI, so it's a good idea to allow XMC through. Not 100% sure on NAC, but if your workflows aren't working or you're having issues with enforcing from XMC/NAC, I'd add the NAC IP as well.