Not at all, the PoE handshakes start with a signature detection of about 25k Ohms to determine if the device at the PD end is PoE capable. If no signature is detected, the port functions as a regular port.
You will see logs if you exceed PoE thresholds or if you get a PoE fault etc. PCs will not use PoE or won't try to negotiate with the switch to do PoE.
Does that help? Or do you have more questions that I can answer