From the Cisco website (http://www.cisco.com/c/en/us/td/docs/security/ise/1-2/compatibility/ise_sdt.html): Certain advanced use cases, such as those that involve posture assessment, profiling, and web authentication, are not consistently available with non-Cisco devices or may provide limited functionality, and are therefore not supported with non-Cisco devices. In addition, certain other advanced functions like central web authentication (CWA), Change of Authorization (CoA), Security Group Access (SGA), and downloadable access control lists (ACLs), are only supported on Cisco devices. So I guess it depends on what you are wanting to do/achieve. But according to the documentation basic authentication should not be a problem as it is all RADIUS standards.