If you have auto Tx control enabled, you should verify that you have the RF domain setup appropriately on each AP. Typically you would have one RF domain for 5.0Ghz and one for 2.4Ghz in each building, which means that all of the AP's in the building would send out probes and adjust their signal strength based on the closest neighboring AP's. If the neighboring AP's are not in the same RF domain, they will most likely default to the max allowed strength. This could cause a whole lot of channel overlap in the environment you described. You could also manually set the channel's and power, however you would need a good tool to do this correctly, something like Ekahau site survey or Fluke Airmagnet.
You can also look at your DCS settings and Ap logs as well to determine which AP's are getting slammed by interference.