Hi Thavamani,
As far as i have checked, the APP which you are mentioning uses very common ports and mask the packets, so blocking the usage with port numbers may not be a handy option where you will also end up blocking the protocols which are commonly used in the network.
User views on the APP states that blocking this app traffic is possible via deep inspection of packets using a firewall.
More info is available in this discussion.
https://networkengineering.stackexchange.com/questions/22881/how-i-can-block-psiphon
This is my View unless someone else have achieved blocking these traffic in any other way, lets wait and see.
